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To a solution of 1,1-dimethylethyl
(86.0 g, 0.266 mol) in THF (600 mL) at 0 0C was added LiAlH4 (13.17 g, 0.347 mol). The reaction mixture was stirred at 0 0C for 1 h, quenched with Na2SO4-IO H2O (40.0 g in 600 mL of water), and stirred for an additional 2 h. The reaction mixture was diluted with Et2O (200 mL) and the layers were separated. The aqueous layer was extracted with Et2O (3 x 200 mL). The combined organic layers were washed with 1 M aq. HCl (2 x 100 mL), saturated aq. NaHCO3 (2 x 100 mL), and brine, dried over Na2SO4,
filtered, and concentrated in vacuo to afford the title compound (60 g,
86%), which was carried to the next step without further purification. 1H NMR (400 MHz, DMSO-J6) δ ppm 9.55 (s, IH), 7.30 - 7.18 (m, 5H), 5.08 (d, 2H), 4.25 (m, IH), 2.71 (m, IH), 2.24 (m, IH), 1.84 (m, IH), 1.46 (s, 9H).