WO2021205354 - NOVEL NATURE-INSPIRED ANTICANCER AND ANTIBACTERIAL MOTIFS AND PHARMACEUTICAL COMPOSITION THEREOF
NOVEL NATURE-INSPIRED ANTICANCER AND ANTIBACTERIAL MOTIFS AND PHARMACEUTICAL COMPOSITION THEREOF
UNIVERSITY OF SHARJAH
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2021205354&_cid=P12-KZJPKP-63707-1
ApplicantsUNIVERSITY OF SHARJAH
InventorsALTEL, Taleb H.
here is provided novel anticancer and antibacterial compounds, pharmaceutically acceptable salts thereof, and processes for their preparation. The compounds have anticancer activity, which results in the reduction of tumour cell proliferation, enhances cancers cells apoptosis and regulation of iron signalling. The compounds are also particularly active against various Gram-negative and Gram-positive multidrug-resistant bacteria, such as extended-spectrum beta-lactamase (ESBL) producing and colistin-resistant Escherichia coli, carbapenem-resistant E. coli, carbapenem-resistant Acinetobacter baumannii, and methicillin-resistant Staphylococcus aureus (MRSA) including those with reduced susceptibility to many control antibiotics.
here is provided novel anticancer and antibacterial compounds, pharmaceutically acceptable salts thereof, and processes for their preparation. The compounds have anticancer activity, which results in the reduction of tumour cell proliferation, enhances cancers cells apoptosis and regulation of iron signalling. The compounds are also particularly active against various Gram-negative and Gram-positive multidrug-resistant bacteria, such as extended-spectrum beta-lactamase (ESBL) producing and colistin-resistant Escherichia coli, carbapenem-resistant E. coli, carbapenem-resistant Acinetobacter baumannii, and methicillin-resistant Staphylococcus aureus (MRSA) including those with reduced susceptibility to many control antibiotics.
