WO-2014199244
Crystalline imatinib mesylate process
Shilpa Medicare Ltd
| Inventors: | PIPAL, Bhagat Raj VEERESHAPPA, Mr. SHARMA, Manish CHATURVEDI, Akshay, Kant |
| Title: | CRYSTALLINE IMATINIB MESYLATE PROCESS |
| Abstract: |
The present invention relates to a process for
preparation of crystalline non-needle shaped Form-SA of Imatinib
mesylate (I).(Formula I) (I) The invention also relates to crystalline
Form-SA obtained by the process of the present invention, the said
Form-SA being substantially pure, stable, non-needle shaped and
characterized by X-ray powder diffraction pattern comprising of atleast
five 20° peaks selected from 10.67, 12.90, 15.34, 19.49, 19.80, 26.06,
26.32 and 28.89 ± 0.05 2Θ°. The invention further relates to
pharmaceutical compositions comprising non-needle shaped crystalline
Form-SA of Imatinib mesylate, useful for the treatment of cancer.
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