NEW PATENT.......WO 2014199244 ....Crystalline imatinib mesylate process

WO-2014199244
 Crystalline imatinib mesylate process
Shilpa Medicare Ltd

Inventors:	PIPAL, Bhagat Raj VEERESHAPPA, Mr. SHARMA, Manish CHATURVEDI, Akshay, Kant
Title:	CRYSTALLINE IMATINIB MESYLATE PROCESS
Abstract:	The present invention relates to a process for preparation of crystalline non-needle shaped Form-SA of Imatinib mesylate (I).(Formula I) (I) The invention also relates to crystalline Form-SA obtained by the process of the present invention, the said Form-SA being substantially pure, stable, non-needle shaped and characterized by X-ray powder diffraction pattern comprising of atleast five 20° peaks selected from 10.67, 12.90, 15.34, 19.49, 19.80, 26.06, 26.32 and 28.89 ± 0.05 2Θ°. The invention further relates to pharmaceutical compositions comprising non-needle shaped crystalline Form-SA of Imatinib mesylate, useful for the treatment of cancer.

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